2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-114763
    LP8
    		Inhibitor
    LP8 is a Pyridinyl-type CYP51 inhibitor and can be used for study of chagas disease and American trypanosomiasis.
    LP8
  • HY-159963
    PfCLK3-IN-1
    		Inhibitor
    PfCLK3-IN-1 (Compound 4) is a covalent inhibitor for Plasmodium falciparum CLK3 (Pf CLK3) under alkaline conditions with an pEC50 of 7.1. PfCLK3-IN-1 reduces mature gametocytes in sexual stage parasites, and prevents transmission. PfCLK3-IN-1 inhibits P. falciparum Dd2-B2 clone with an IC50 of 239.5 nM.
    PfCLK3-IN-1
  • HY-170783
    DXR-IN-4
    		Inhibitor
    DXR-IN-4 (Compound 12a) is the inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). DXR-IN-4 inhibits DXR in Plasmodium falciparum Pf DXR, Escherichia coli Ec DXR, and Mycobacterium tuberculosis Mt DXR with IC50s of 18, 4.9 and 89 nM, respectively. DXR-IN-4 exhibits antimalarial activity that inhibits P. falciparum strains 3D7 and Dd2 with IC50 of 11 μM and 12 μM.
    DXR-IN-4
  • HY-124018
    MMV665852
    		Inhibitor
    MMV665852 is an antischistosomal agent that inhibits worm viability in vitro. MMV665852 reduces worm burden in mice infected with Schistosoma mansoni.
    MMV665852
  • HY-175246
    Antitoxoplasmal agent-1
    		Inhibitor
    Antitoxoplasmal agent-1 (Compound 4) is an antiparasitic agent. Antitoxoplasmal agent-1 has strong activity and selectivity against T. gondii, with an IC50 of 3.1 μM. Antitoxoplasmal agent-1 also has certain activity against L. major amastigotes, with an EC50 of 23.3 μM. Antitoxoplasmal agent-1 can be used in the research of parasite-related diseases.
    Antitoxoplasmal agent-1
  • HY-177539
    ent-Epanorin
    		Inhibitor
    ent-Epanorin is an enantiomer of Epanorin (HY-N16418). ent-Epanorin has more potent antibacterial and antiparasitic activity against Bacillus subtilis (ATCC 6633), Staphylococcus aureus (ATCC 25923) and Giardiaduodenalis 713 compared to Epanorin.
    ent-Epanorin
  • HY-B1177R
    Crotamiton (Standard)
    		Inhibitor
    Crotamiton (Standard) is the analytical standard of Crotamiton. This product is intended for research and analytical applications.
    Crotamiton (Standard)
  • HY-W011035R
    Dodecamethylpentasiloxane (Standard)
    		Inhibitor
    Dodecamethylpentasiloxane (Standard) is the analytical standard of Dodecamethylpentasiloxane. This product is intended for research and analytical applications. Dodecamethylpentasiloxane is a component of siloxanes and can be used as silicone oil. Dodecamethylpentasiloxane exhibits insecticidal activity against bed bug.
    Dodecamethylpentasiloxane (Standard)
  • HY-169922
    HDAC-IN-82
    		Inhibitor
    HDAC-IN-82 (Compound 18b) is a histone deacetylase (HDAC) inhibitor with selective antiplasmodial and anticancer activity. HDAC-IN-82 shows potent antiproliferative activity and caspase 3/7 activation in cancer cells. HDAC-IN-82 causes hyperacetylation of histone H3 and α-tubulin.
    HDAC-IN-82
  • HY-175215
    PfPK6-IN-1
    PfPK6-IN-1 is a potent and selective PfPK6 inhibitor with an IC50 of 0.3 μM. PfPK6-IN-1 inhibits hemozoin formation, a Plasmodium-specific pathway with IC50 of 13 μM against β-hematin (βH). PfPK6-IN-1 exhibits rapid and broad-spectrum anti-malarial properties, being effective against both chloroquine-sensitive and resistant strains.PfPK6-IN-1 can be used for the study of antimalarial.
    PfPK6-IN-1
  • HY-15980
    GNF179 (Metabolite)
    		Inhibitor
    GNF179 metabolite is the metabolite of GNF179, which is an optimized 8,8-dimethyl IP analog that exhibited the potency(4.
    GNF179 (Metabolite)
  • HY-N11761
    4,5-Dihydropiperlonguminine
    		Inhibitor
    4,5-Dihydropiperlonguminine is a natural product that can be isolated from the seeds of Piper tuberculatum Jacq. (Piperaceae). 4,5-Dihydropiperlonguminine is a insecticide against velvetbean caterpillars.
    4,5-Dihydropiperlonguminine
  • HY-148177
    Sutidiazine
    		Inhibitor
    Sutidiazine (ZY-19489) is an orally active and antimalarial agent. Sutidiazine inhibits parasitemia-induced infection. Sutidiazine shows short half-lives (approximately 7 h) and an exposure effect.
    Sutidiazine
  • HY-107496R
    Imidocarb dipropionate (Standard)
    		Inhibitor
    Imidocarb (dipropionate) (Standard) is the analytical standard of Imidocarb (dipropionate). This product is intended for research and analytical applications. Imidocarb dipropionate is a potent antiprotozoal agent. Imidocarb dipropionate is active against the parasite B. bovis with an IC50 of 87 μg/mL.
    Imidocarb dipropionate (Standard)
  • HY-124901R
    Tetrasul (Standard)
    		Inhibitor
    Tetrasul (Standard) is the analytical standard of Tetrasul. This product is intended for research and analytical applications. Tetrasul is an acaricide. Tetrasul inhibits Tetranychus urticae and aphids on hops. Tetrasul has also been used in research of erythematous (type one) rosacea.
    Tetrasul (Standard)
  • HY-W158234
    N-Methylbenzo[d]oxazol-2-amine
    		Inhibitor
    N-Methylbenzo[d]oxazol-2-amine (compound 1) is an anthelmintic activity and lower cytotoxicity against T. spiralis adult worm. N-Methylbenzo[d]oxazol-2-amine up-regulates the metabolism of purine, pyrimidine and down-regulates sphingolipid metabolism.
    N-Methylbenzo[d]oxazol-2-amine
  • HY-175181
    SufS-IN-1
    		Inhibitor
    SufS-IN-1, a (2R,3R)-3-ethoxycarbonylaziridine-2-carboxylic acid (EAC), is a selective Cysteine desulfurase type II (SufS) inhibitor. SufS-IN-1 significantly inhibits the SufS activity by covalently binding to the cofactor PLP to form a stable PLP-ligand conjugates. SufS-IN-1 can be used for pathogenic microorganisms research, such as Plasmodium falciparum, Staphylococcus aureus and Mycobacterium tuberculosis.
    SufS-IN-1
  • HY-157037
    OfChi-h-IN-2
    		Inhibitor
    OfChi-h-IN-2 (compound TQ19) is a potent OfChi-h inhibitor with a Ki value of 0.33 μM. OfChi-h-IN-2 can significantly inhibit the growth and development of Ostrinia nubilalis larvae. OfChi-h-IN-2 can be used in agricultural insecticide research.
    OfChi-h-IN-2
  • HY-121618R
    α-Thujone (Standard)
    		Inhibitor
    α-Thujone (Standard) is the analytical standard of α-Thujone. This product is intended for research and analytical applications. α-Thujone is a monoterpene isolated from Thuja occidentalis essential oil with potent anti-tumor activities. α-Thujone is a reversible modulator of the GABA type A receptor and the IC50 for α-Thujone is 21 μM in suppressing the GABA-induced currents. α-Thujone induces ROS accumulation-dependent cytotoxicity, also induces cell apoptosis and autophagy. α-Thujone has antinociceptive, insecticidal, and anthelmintic activity, and easily penetrates the blood-brain barrier.
    α-Thujone (Standard)
  • HY-17581R
    Buparvaquone (Standard)
    		Inhibitor
    Buparvaquone (Standard) is the analytical standard of Buparvaquone. This product is intended for research and analytical applications. Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone.
    Buparvaquone (Standard)
Parasite Isoform Comparison

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